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Henry Rzepa's Blog

Henry Rzepa's Blog
Chemistry with a twist
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I promised that the follow-up to on the topic of Birch reduction would focus on the proton transfer reaction between the radical anion of anisole and a proton source, as part of analysing whether the mechanistic pathway proceeds O or M . To add some context, Hammond’s postulate [cite]10.1021/ja01607a027[/cite] states that “ the structure of a transition state resembles that of the species